Brand new, sealed and authentic with box. Bought extra for myself and letting go. 2 available. This is a generic version of retin a micro, works exactly the same and same active ingredient. This is better then normal retin a as it is less irritating and just as effective. Only will be sold to people who has been using and currently use retin a and know how to use it properly. Not for beginners looking for a quick fix that are unfamiliar with the product. -- The main difference between Retin-A and Retin-A Micro is the following: Retin-A: A cream with a given concentration of tretinoin. Delivers all of the ingredient all at once. Retin-A Micro: A lightweight gel with a given concentration of tretinoin packaged in microspheres for a sustained time-release. Retin-A: You must wait 20-30 minutes after washing your face before applying. Retin-A Micro: You can apply immediately after washing your face. Retin-A: Risk of irritation is significantly higher. Retin-A Micro: Risk of irritation is significantly lower. Microspheres help the ingredient to slowly diffuse into the skin, rather than applied all at once. Bottom Line: Retin-A Micro is better – the sustained release enables the retinoid to be active in your skin longer. It is also superior in particular for oily and sensitive skin types, because there is more shine reduction and less irritation potential than with traditional Retin-A. ~ If you have questions please do ask me. Advise you to do your research on retin a skincare before using. This is the gold bullet standard for skin care and it is good for acne, pimples , melasma , anti aging , wrinkles , pigmentation , scars , whitening and dark marks . Regular use increases collagen and evens out skin tone. Also better than standard retinol products from roc and paulas choice for example. Touted as one of the most effective products to lessen the appearance and magnitude of acne. While blackheads and pimples, as well as other acne symptoms, would normally be difficult to eliminate, Tretinoin efficiently does so. Recommended Use Always use spf in the day time. Apply in the evening or just before going to bed. Apply a pea size amount of tretinoin to your face. Avoid contact with the mouth, eyes, and nostrils. It's very common for peeling and redness to occur if used too soon or too much.